Spyre Therapeutics Down Over 12%, On Pace For Largest Percent Decrease Since June 2024 -- Data Talk

Spyre Therapeutics, Inc (SYRE) is currently at $94.12, down $13.24 or 12.33%

--Would be lowest close since July 16, 2026, when it closed at $94.12

--On pace for largest percent decrease since June 17, 2024, when it fell 19.3%

--Snaps a two day winning streak

--Down 4.28% month-to-date; on pace for worst month since April 2025, when it fell 5.61%

--Up 187.3% year-to-date

--Down 68.6% from its all-time closing high of $299.75 on April 8, 2016

--Up 449.12% from 52 weeks ago (Aug. 27, 2025), when it closed at $17.14

--Down 13.59% from its 52-week closing high of $108.92 on Aug. 19, 2026

--Up 535.09% from its 52-week closing low of $14.82 on Sept. 16, 2025

--Traded as low as $90.60; lowest intraday level since July 7, 2026, when it hit $86.60

--Down 15.61% at today's intraday low; largest intraday percent decrease since June 24, 2026, when it fell as much as 15.87%

All data as of 10:32:24 AM ET

Source: Dow Jones Market Data, FactSet

(END) Dow Jones Newswires

August 26, 2026 10:35 ET (14:35 GMT)