MacroGenics Presents MGC026 Data Showing 27.3% Best Overall Response Rate in Head and Neck Cancer
Bitget2026/10/27 14:08- MacroGenics presented MGC026 data at ESMO showing a 27.3% best overall response rate in 22 heavily pretreated head-and-neck cancer patients.
- Confirmed responses reached 18.2%; the disease control rate was 63.6%.
- No treatment-related discontinuations occurred in the 27-patient expansion cohort; no interstitial lung disease, pneumonitis or ocular toxicity was reported.
- A front-line MGC026-pembrolizumab combination study is planned for early 2027, with the next MGC026 update anticipated mid-2027.
- Pro forma cash equivalents and marketable securities totaled $327 million, supporting a projected cash runway through 2028.
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