Lyell Immunopharma's Ronde-Cel Achieves 77% Complete Response Rate in Pivotal Lymphoma Trial
Bitget2026/11/04 14:11- Lyell Immunopharma will present updated ronde-cel lymphoma trial results at the American Society of Hematology meeting, December 12-15, 2026.
- Previously disclosed results showed high complete response rates and durable remissions in second-line and later-line relapsed or refractory large B-cell lymphoma.
- No severe cytokine release syndrome occurred in either cohort; severe neurotoxicity was uncommon, supporting potential outpatient administration.
- The pivotal PiNACLE trial is intended to support an initial application for regular marketing approval.
- A separate randomized Phase 3 trial compares ronde-cel with approved CD19-directed CAR T-cell therapies in second-line treatment.
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