Market Chatter: AstraZeneca Makes $10 Billion Offer for Rhythm Pharmaceuticals

04:07 AM EST, 11/05/2026 (MT Newswires) -- AstraZeneca (AZN) has made an offer of about $10 billion to acquire Rhythm Pharmaceuticals (RYTM) for $124 per share, the Wall Street Journal reported Wednesday, citing people familiar with the matter. The offer, made last month, would expand AstraZeneca's portfolio of rare-disease and obesity treatments as it seeks to reach $80 billion in annual sales by 2030, the report said. An AstraZeneca spokesperson declined to comment, Rhythm Pharmaceuticals did not immediately respond to MT Newswires' request for comment. (Market Chatter news is derived from conversations with market professionals globally. This information is believed to be from reliable sources but may include rumor and speculation. Accuracy is not guaranteed.)